EDUCATE
WHAT IS CBD?
UNDERSTANDING CBD AND HEMP PLANTS
CBD (Cannabidiol) is a chemical compound found in the hemp plant, known for its various uses. Both cannabis and hemp plants contain over 100 organic compounds known as cannabinoids, with the two most abundant being THC (Tetrahydrocannabinol) and CBD.
DISTINGUISHING CANNABIS FROM HEMP
The primary difference between cannabis and hemp plants lies in the concentration of these compounds:
- Cannabis is classified as marijuana if it contains more than 0.3% THC.
- Hemp, on the other hand, is considered industrial hemp if it has 0.3% THC or less.
EFFECTS OF THC AND CBD
- THC: High levels of THC are responsible for the "high" or intoxicating effect associated with marijuana.
- CBD: Industrial hemp is bred to have high CBD and low THC, providing therapeutic benefits without causing a high.
HEALTH BENEFITS AND THE ENTOURAGE EFFECT
Since the FDA approved the first CBD medication, numerous studies have demonstrated the positive effects of CBD and other cannabinoids. Research also shows that:
- CBD and other cannabinoids work together with compounds like terpenes and flavonoids.
- This interaction creates a synergistic effect known as the "entourage effect."
IMPORTANCE OF SPECIFIC RATIOS
The effectiveness of a CBD product is influenced by the specific ratios of CBD and other compounds, not just the amount of CBD present. Proper formulation is crucial for achieving superior therapeutic benefits.
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HOW CBD WORKS
HOW CBD WORKS: MECHANISMS AND EFFECTS
CBD (Cannabidiol) is one of the many cannabinoids found in the cannabis plant. Unlike THC, CBD does not produce a "high" or intoxicating effect. Instead, it interacts with the body's endocannabinoid system (ECS), which plays a crucial role in maintaining homeostasis or balance within the body.
INTERACTION WITH THE ENDOCANNABINOID SYSTEM
The ECS consists of three main components:
- Endocannabinoids: Naturally occurring compounds in the body similar to cannabinoids found in cannabis.
- Receptors: CB1 and CB2 receptors located throughout the body.
- Enzymes: Responsible for breaking down endocannabinoids after they have fulfilled their function.
CB1 receptors are primarily found in the brain and central nervous system and are associated with mood, appetite, pain sensation, and memory. CB2 receptors are mainly located in the peripheral organs and are involved in immune system regulation and inflammation.
CBD interacts with the ECS by:
- Modulating receptor activity: Unlike THC, which binds directly to CB1 receptors, CBD does not directly bind to these receptors. Instead, it influences the receptors' activity, enhancing or inhibiting their function as needed.
- Inhibiting enzyme activity: CBD inhibits the activity of the enzyme FAAH (fatty acid amide hydrolase), which breaks down anandamide, an endocannabinoid known as the "bliss molecule." This inhibition increases anandamide levels in the body, promoting a sense of well-being and balance.
BEYOND THE ECS
CBD also interacts with various non-ECS receptors and molecular pathways:
- Serotonin receptors: CBD binds to the 5-HT1A receptor, which is involved in regulating mood, anxiety, and stress. This interaction can explain CBD's potential anti-anxiety and antidepressant effects.
- TRPV1 receptors: These receptors, involved in pain perception and inflammation, are activated by CBD, potentially contributing to its analgesic and anti-inflammatory properties.
- PPARs (peroxisome proliferator-activated receptors): Activation of these receptors by CBD can influence lipid metabolism and glucose homeostasis, providing potential benefits for metabolic disorders.
THERAPEUTIC EFFECTS
Through these interactions, CBD offers various therapeutic effects, including:
- Anti-inflammatory: Reduces inflammation by modulating immune responses.
- Analgesic: Alleviates pain through multiple pathways.
- Anxiolytic and antidepressant: Reduces anxiety and improves mood by influencing serotonin and other neurotransmitter systems.
- Neuroprotective: Protects neurons and supports brain health, potentially benefiting conditions like epilepsy and neurodegenerative diseases.
In summary, CBD works by interacting with the endocannabinoid system and other molecular pathways, influencing a range of physiological processes to promote balance and well-being.
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CBD FOR SKIN: BENEFITS AND USES
CBD (Cannabidiol) has gained popularity in skincare due to its numerous beneficial properties. Here's how CBD can benefit the skin:
ANTI-INFLAMMATORY PROPERTIES
CBD is well-known for its anti-inflammatory effects. When applied topically, it can help reduce inflammation and redness, making it beneficial for conditions like acne, eczema, and psoriasis. By interacting with the endocannabinoid system, CBD helps regulate the skin's inflammatory response, leading to calmer and less irritated skin.
ANTIOXIDANT EFFECTS
CBD is rich in antioxidants, which protect the skin from damage caused by free radicals. Free radicals can accelerate the aging process by breaking down collagen and elastin, leading to wrinkles and fine lines. Using CBD-infused skincare products can help neutralize these free radicals, promoting healthier and more youthful skin.
SEBUM REGULATION
Excess sebum production is a major cause of acne. CBD has been shown to regulate sebum production, reducing the likelihood of clogged pores and breakouts. Its balancing effect on oil production makes it suitable for both oily and dry skin types.
HYDRATION AND NOURISHMENT
CBD contains essential fatty acids, such as omega-3 and omega-6, which provide deep hydration and nourishment to the skin. These fatty acids help maintain the skin's natural barrier, keeping it moisturized and protected from environmental stressors.
HEALING AND SOOTHING
CBD has soothing properties that can help alleviate discomfort and promote healing. It is effective in reducing the symptoms of skin conditions like dermatitis and can aid in the recovery of damaged skin.
USAGE
CBD can be found in various skincare products, including creams, serums, balms, and oils. For best results, choose high-quality, reputable products and follow the recommended usage instructions.
In summary, CBD offers a holistic approach to skincare by leveraging its anti-inflammatory, antioxidant, and hydrating properties, making it a versatile and beneficial ingredient for maintaining healthy skin.
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CBD AND OTHER CANNABINOIDS: A COMPREHENSIVE OVERVIEW
CBD is just one of over 100 cannabinoids found in the cannabis plant. Each cannabinoid interacts with the body in unique ways, contributing to a variety of therapeutic effects. Here's an overview of CBD and some other notable cannabinoids:
CANNABIDIOL (CBD)
CBD is non-psychoactive, meaning it doesn't produce the "high" associated with THC. It offers numerous health benefits:
- Anti-inflammatory: Reduces inflammation, beneficial for conditions like arthritis and acne.
- Anxiolytic: Alleviates anxiety and stress.
- Antiepileptic: Reduces the frequency of seizures in epilepsy.
- Pain relief: Manages chronic pain through various mechanisms.
CANNABINOL (CBN)
CBN is a mildly psychoactive cannabinoid formed as THC ages:
- Sedative: Promotes sleep, making it useful for insomnia.
- Pain relief: Provides analgesic effects.
- Anti-inflammatory: Helps reduce inflammation.
CANNABIGEROL (CBG)
CBG is known as the "mother of all cannabinoids" because other cannabinoids derive from it:
- Antibacterial: Fights bacterial infections.
- Anti-inflammatory: Reduces inflammation.
- Neuroprotective: Supports brain health and may protect against neurodegenerative diseases.
CANNABICHROMENE (CBC)
CBC is non-psychoactive and works synergistically with other cannabinoids:
- Anti-inflammatory: Reduces inflammation without psychoactive effects.
- Antidepressant: Elevates mood by interacting with the brain's receptors.
- Pain relief: Contributes to analgesic effects.
THE ENTOURAGE EFFECT
The combined effect of cannabinoids working together is known as the entourage effect. This synergy enhances the therapeutic benefits of each individual cannabinoid. For example, CBD can mitigate the psychoactive effects of THC while enhancing its pain-relieving properties. Similarly, the presence of minor cannabinoids like CBN, CBG, and CBC can amplify the overall effectiveness of CBD.
CONCLUSION
Understanding the diverse roles of cannabinoids helps in formulating effective treatments for a variety of conditions. The entourage effect underscores the importance of using full-spectrum or broad-spectrum CBD products to harness the full therapeutic potential of the cannabis plant.
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Frequently Asked Questions
Understanding Our Extracts
Full Spectrum Oil is a whole-plant hemp extract that preserves the complete cannabinoid profile — CBD, CBG, CBN, CBDA, and trace cannabinoids — along with terpenes and up to 0.3% THC. It's the extract most associated with the entourage effect, the idea that hemp's compounds work better together than in isolation. Note: FSO products carry a risk of returning a positive drug test result.
CBD isolate is hemp's purest form — a crystalline powder refined to a single compound at 99%+ purity, with all other cannabinoids and terpenes removed. Isolates only reach their full potential when paired with other cannabinoids and terpenes, which is why Midori uses them as building blocks rather than a finished ingredient.
Broad spectrum CBD contains multiple cannabinoids and terpenes but has been refined to remove detectable THC. Rather than using a pre-made broad spectrum extract, Midori builds its own — combining individual cannabinoid isolates at precise ratios to create what we call the Midori Broad Spectrum. This approach lets us specify the exact milligram amount of each cannabinoid in every formula, rather than working from an estimate. Each blend is then enhanced with a curated selection of plant-derived terpenes to deepen the entourage effect and define each product's botanical character.
The entourage effect is the theory that hemp's cannabinoids, terpenes, and phytochemicals work more effectively together than any single compound does in isolation. Research is ongoing, but it's the foundation of Midori's formulation philosophy — using precisely built broad spectrum blends and curated terpene profiles to preserve the plant's full botanical complexity.
Terpenes are the naturally occurring aromatic compounds that give plants their distinctive scents — hemp contains over 100, including linalool, myrcene, limonene, and beta-caryophyllene. Beyond their sensory role, terpenes are thought to interact with the endocannabinoid system and influence how cannabinoids are experienced. Midori selects and blends specific plant-derived terpenes into each formulation to support its intended character.
Our Cannabinoids
Cannabigerol (CBG) is the biosynthetic precursor to CBD, THC, and other cannabinoids — making it relatively rare in finished extracts. It interacts with the endocannabinoid system through a distinct mechanism from CBD, and Midori incorporates it into select formulations to broaden the cannabinoid profile for a more complete botanical experience.
Cannabinol (CBN) is a mildly active cannabinoid that forms as THC oxidizes in the hemp plant over time. It's best known for its association with evening wellness routines, and Midori includes it in restorative formulations alongside chamomile, passionflower, and a curated nighttime terpene blend.
Cannabidiolic acid (CBDA) is the raw, unheated precursor to CBD found in fresh hemp — it converts to CBD through decarboxylation. CBDA interacts with serotonin receptors and COX-2 enzymes through mechanisms distinct from CBD, and Midori uses it in select formulations to keep the extract closer to the plant's native chemistry.
Researchers are actively studying CBD's interaction with the endocannabinoid system, a regulatory network involved in processes including sleep, mood, appetite, skin balance, and the body's response to physical stress. Many people incorporate CBD into daily wellness routines for its botanical properties and the sense of balance they associate with consistent use. Midori products are designed to support everyday wellness — not to treat any medical condition.
Our Products & Formulations
Every Midori formula is built on the Midori Broad Spectrum — a proprietary blend of individual cannabinoid isolates (CBD, CBG, CBN, and CBDA depending on the formula) combined at precise, performance-driven ratios. Because we start from isolates rather than a pre-blended extract, we can guarantee the exact milligram amount of each cannabinoid in every product. This foundation is then elevated with plant-derived terpenes and a curated set of functional botanicals, each chosen for their complementary role in the formula. Every ingredient has a purpose; nothing is decorative.
Topicals are applied directly to the skin, where cannabinoids interact with local receptors without entering the bloodstream in meaningful amounts — making them well-suited for targeted use. Ingestibles are processed through the digestive system and work systemically, with a slower onset and longer duration. Many people use both as complementary parts of a broader wellness routine.
Yes. Midori's formulations contain no animal-derived ingredients and are never tested on animals. For full ingredient information, refer to the INCI list on each product page.
Yes — Midori products are designed to integrate into an existing routine, and our botanical actives are well-established in professional formulation. If you take prescription medications or have specific skin sensitivities, consult a healthcare professional before adding new actives. A patch test is always advisable for reactive skin.
Dosing & How to Use
There's no universal CBD dose — the right amount depends on body weight, metabolism, and the specific product and concentration. Start low, observe your response over several days, and adjust incrementally.
For most adults new to CBD ingestibles, 25 –50mg per day is a common starting point, taken consistently at the same time each day. If you don't notice a response after five to seven days, increase gradually. Because CBD accumulates with regular use, allow at least two weeks before assessing whether a dose is right for you.
For ingestibles, once or twice daily — morning and evening — is the most common approach, helping maintain a steady level in the system. Topicals can be applied as needed to the area of focus at any time of day.
Topicals typically produce a localized effect within 15–45 minutes of application. Ingestibles generally take 30 minutes to 1 hour to take effect, with results lasting four to six hours or longer. Longer-term effects from consistent use are typically observed over weeks, as cannabinoids accumulate in the body's lipid-rich tissues.
Safety & Testing
Yes. All Midori products are tested by independent, accredited laboratories for cannabinoid content, THC levels, and contaminants including pesticides, heavy metals, residual solvents, and microbial impurities. Certificates of Analysis (COAs) can be found in the About Us drop down.
Midori's broad spectrum extracts are processed to bring THC to non-detectable levels, and standard drug tests screen for THC metabolites — not CBD. That said, no hemp-derived product can guarantee a negative result; individual factors like frequency of use and body composition affect outcomes. If you're subject to regular testing, review the product COA and consult your testing administrator before use.